V 2 C Nanosheets as Dual-Functional Antibacterial Agents

作者：Shah Zada, Huiting Lu, Fanwen Yang, Yiyi Zhang, Yaru Cheng, Songsong Tang, Wei Wei, Yuchun Qiao, Pengcheng Fu, Haifeng Dong, Xueji Zhang · 发表于：ACS Applied Bio Materials · 年份：2021 · DOI：10.1021/acsabm.1c00008 · 被引用次数：45 · 研究领域：MXene and MAX Phase Materials、Advanced Photocatalysis Techniques、2D Materials and Applications

Antibiotic-resistant bacterial strains have been continuously increasing and becoming a supreme threat to public health globally. The nanoparticle-based photothermal treatment has emerged as a powerful tool to combat toxic bacteria. Photothermal agents (PTAs) with cost-effective and high photothermal conversion efficiency are highly desirable. Herein, we unite the green process for delamination of V 2 AlC to produce a high yield mass of two-dimensional (2D) V 2 C nanosheets (NSs) by using algae extracts and demonstrate their high antibacterial efficiency. The resultant V 2 C NSs present decent structural reliability and intrinsic antibacterial ability. Powerful near-infrared (NIR) absorption and extraordinary photothermal conversion proficiency make it a good PTA for the photothermal treatment of bacteria. The antibacterial efficiency evaluation indicated that V 2 C NSs could effectively kill both Gram-positive S. aureus and Gram-negative E. coli . About 99.5% of both types of bacteria could be killed with low-dose of V 2 C NSs suspension (40 μg/mL) with 5 min NIR irradiation due to the intrinsic antibacterial ability and photothermal effect of V 2 C NSs, which is much higher than previous reports on Ta 4 C 3, Ti 3 C 2, MoSe 2, and Nb 2 C. This work expands the application of MXene V 2 C NSs for rapid bacteria-killing and would gain promising attention for applications in the sterilization industry.