Green Esterification of Carboxylic Acids Promoted by tert ‐Butyl Nitrite

作者：Yonggao Zheng, Yanwei Zhao, Suyan Tao, Xingxing Li, Xionglve Cheng, Gangzhong Jiang, Xiaobing Wan · 发表于：European Journal of Organic Chemistry · 年份：2021 · DOI：10.1002/ejoc.202100326 · 被引用次数：23 · 研究领域：Chemical Synthesis and Reactions、Sulfur-Based Synthesis Techniques、Asymmetric Hydrogenation and Catalysis

Abstract In this work, the green esterification of carboxylic acids promoted by tert‐ butyl nitrite has been well developed. This transformation is compatible with a broad range of substrates and exhibits excellent functional group tolerance. Various drugs and substituted amino acids are applicable to this reaction under near neutral conditions, with good to excellent yields.