Bacteria-driven phthalic acid ester biodegradation: Current status and emerging opportunities

作者：Ruiwen Hu, Hai-Ming Zhao, Xihui Xu, Zhigang Wang, Ke Yu, Longfei Shu, Qingyun Yan, Bo Wu, Ce-Hui Mo, Zhili He, Cheng Wang · 发表于：Environment International · 年份：2021 · DOI：10.1016/j.envint.2021.106560 · 被引用次数：169 · 研究领域：Microbial Metabolic Engineering and Bioproduction、3D Printing in Biomedical Research、Amino Acid Enzymes and Metabolism

The extensive use of phthalic acid esters (PAEs) has led to their widespread distribution across various environments. As PAEs pose significant threats to human health, it is urgent to develop efficient strategies to eliminate them from environments. Bacteria-driven PAE biodegradation has been considered as an inexpensive yet effective strategy to restore the contaminated environments. Despite great advances in bacterial culturing and sequencing, the inherent complexity of indigenous microbial community hinders us to mechanistically understand in situ PAE biodegradation and efficiently harness the degrading power of bacteria. The synthetic microbial ecology provides us a simple and controllable model system to address this problem. In this review, we focus on the current progress of PAE biodegradation mediated by bacterial isolates and indigenous bacterial communities, and discuss the prospective of synthetic PAE-degrading bacterial communities in PAE biodegradation research. It is anticipated that the theories and approaches of synthetic microbial ecology will revolutionize the study of bacteria-driven PAE biodegradation and provide novel insights for developing effective bioremediation solutions.