Clinical characteristics, medical service utilization, and expenditure for colorectal cancer in China, 2005 to 2014: Overall design and results from a multicenter retrospective epidemiologic survey

作者：Jufang Shi, Le Wang, Jian‐Chao Ran, Hong Wang, Chengcheng Liu, Haizeng Zhang, Lin Yang, Su‐Sheng Shi, Liming Jiang, Jin‐Hu Fan, Yue‐Ming Zhang, Weihu Wang, Jiansong Ren, Lin Zhu, Zhaoxu Zheng, Yongkun Sun, Shuangmei Zou, Jun Jiang, Bo Chen, Hongda Chen, Guoxiang Liu, Li Yang, Yunchao Huang, Lan‐Wei Guo, Debin Wang, Yong‐Zhen Zhang, Ayan Mao, Jialin Wang, Jiyong Gong, Donghua Wei, Wu‐Qi Qiu, Bingbing Song, Kai Zhang, Ni Li, Eleonora Feletto, Jie‐Bin Lew, You‐Lin Qiao, Wanqing Chen, Min Dai, Jie He · 发表于：Cancer · 年份：2021 · DOI：10.1002/cncr.33445 · 被引用次数：109 · 研究领域：Colorectal Cancer Screening and Detection、Economic and Financial Impacts of Cancer、Global Cancer Incidence and Screening

BACKGROUND: Colorectal cancer (CRC) is the third most common cancer in China, however, publicly available, descriptive information on the clinical epidemiology of CRC is limited. METHODS: Patients diagnosed with primary CRC during 2005 through 2014 were sampled from 13 tertiary hospitals in 9 provinces across China. Data related to sociodemographic characteristics, the use of diagnostic technology, treatment adoption, and expenditure were extracted from individual medical records. RESULTS: In the full cohort of 8465 patients, the mean ± SD age at diagnosis was 59.3 ± 12.8 years, 57.2% were men, and 58.7% had rectal cancer. On average, 14.4% of patients were diagnosed with stage IV disease, and this proportion increased from 13.5% in 2005 to 20.5% in 2014 (P value for trend < .05). For diagnostic techniques, along with less use of x-rays (average, 81.6%; decreased from 90.0% to 65.7%), there were increases in the use of computed tomography (average, 70.4%; increased from 4.5% to 90.5%) and magnetic resonance imaging (average, 8.8%; increased from 0.1% to 20.4%) over the study period from 2005 to 2014. With regard to treatment, surgery alone was the most common (average, 50.1%), but its use decreased from 51.3% to 39.8% during 2005 through 2014; and the use of other treatments increased simultaneously, such as chemotherapy alone (average, 4.1%; increased from 4.1% to 11.9%). The average medical expenditure per patient was 66,291 Chinese Yuan (2014 value) and increased from 47,2...