Inflammatory Arthritis Induced by Anti-Programmed Death-1 Shown in 68Ga-FAPI PET/CT in a Patient With Esophageal Carcinoma

作者：Yaping Luo, Qingqing Pan, Huaxia Yang, Fang Li, Fengchun Zhang · 发表于：Clinical Nuclear Medicine · 年份：2021 · DOI：10.1097/rlu.0000000000003608 · 被引用次数：33 · 研究领域：Peptidase Inhibition and Analysis、Cardiac Structural Anomalies and Repair、Neuropeptides and Animal Physiology

ABSTRACT: A 30-year-old woman with esophageal squamous cell carcinoma experienced joint pain and swelling in bilateral knees, wrists, and hand joints during the course of neoadjuvant immunochemotherapy. She underwent 18F-FDG and 68Ga-FAPI PET/CT for response assessment of the tumor and evaluating her arthritis. 68Ga-FAPI PET/CT detected intense uptake in multiple joints, consistent with her polyarthritis. However, these joints showed only mild FDG uptake. The tumor was in complete response, and her polyarthritis was considered as inflammatory arthritis induced by anti-PD1.