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Insomnia, Suicidal Ideation, and Suicide Attempts in the Clinical Antipsychotic Trials of Intervention Effectiveness

作者:Brian J. Miller, Joseph P. McEvoy, W. Vaughn McCall · 发表于:The Journal of Clinical Psychiatry · 年份:2021 · DOI:10.4088/jcp.20m13338 · 被引用次数:32 · 研究领域:Sleep and related disorders、Schizophrenia research and treatment、Sleep and Wakefulness Research

Insomnia occurs frequently in the clinical course of schizophrenia. There is a robust association between insomnia and suicide in other psychiatric disorders. Several previous studies found associations between insomnia and suicidal ideation, suicide attempt, and psychopathology in schizophrenia. We explored these associations in a cross-sectional study of a large sample of patients with schizophrenia. schizophrenia trial conducted 2001-2004) using regression models. < .001) scores. There were no other significant associations between insomnia, suicidal thinking or behavior, and psychopathology. Insomnia is associated with suicidal ideation, recent suicide attempt, and greater psychopathology in schizophrenia. Findings provide additional evidence that formal assessment of insomnia is relevant to the clinical care of patients with schizophrenia as an indicator of suicidal ideation and behavior, as well as symptom severity. ClinicalTrials.gov identifier: NCT00014001.