Environmental Candida auris and the Global Warming Emergence Hypothesis

作者：Arturo Casadevall, Dimitrios P. Kontoyiannis, Vincent Robert · 发表于：mBio · 年份：2021 · DOI：10.1128/mbio.00360-21 · 被引用次数：146 · 研究领域：Antifungal resistance and susceptibility、Fungal Infections and Studies、Parasitic Diseases Research and Treatment

Global warming was proposed to be a contributing cause for the nearly simultaneous emergence of different clades of Candida auris as a nosocomial pathogen in different continents. The global warming emergence hypothesis posits that C. auris existed in the environment prior to its clinical recognition and became pathogenic for humans because of thermal adaptation in response to climate change. The isolation of C. auris from two sites in the remote Andaman Islands establishes it as an environmental organism, a necessary condition for the hypothesis.