Distinct placental molecular processes associated with early-onset and late-onset preeclampsia

作者：Zhonglu Ren, Yunfei Gao, Yue Gao, Guanmei Liang, Qian Chen, Sijia Jiang, Xiaoxue Yang, Cui-Xia Fan, Haizhen Wang, Jing Wang, Yi‐Wu Shi, Chaoqun Xiao, Mei Zhong, Xinping Yang · 发表于：Theranostics · 年份：2021 · DOI：10.7150/thno.56141 · 被引用次数：93 · 研究领域：Pregnancy and preeclampsia studies、Birth, Development, and Health、MicroRNA in disease regulation

These results suggest that early-onset and late-onset severe preeclampsia have different molecular mechanisms, whereas the late-onset mild preeclampsia may have no placenta-specific causal factors. A few regulators may be the key drivers of the dysregulated molecular pathways.