Determination, dissipation dynamics, terminal residues and dietary risk assessment of thiophanate‐methyl and its metabolite carbendazim in cowpeas collected from different locations in China under field conditions

作者：Zhengyi Liu, Ye Chen, Jiahua Han, Dan Chen, Guangqian Yang, Tingting Lan, Jianmin Li, Kankan Zhang · 发表于：Journal of the Science of Food and Agriculture · 年份：2021 · DOI：10.1002/jsfa.11198 · 被引用次数：19 · 研究领域：Pesticide Residue Analysis and Safety、Insect and Pesticide Research、Pesticide and Herbicide Environmental Studies

BACKGROUND: Thiophanate-methyl and its metabolite carbendazim are broad-spectrum fungicides used on many crops. The residues of these chemicals could result in potential environmental and human health problems. Therefore, investigations of the dissipation and residue behaviors of thiophanate-methyl and its metabolite carbendazim on cowpeas and associated dietary risk assessments are essential for the safety of agricultural products. RESULTS: > 0.998) was obtained, and the recoveries and relative standard deviations were 80.0-104.7% and 1.4-5.2%, respectively. The dissipation rates of thiophanate-methyl, carbendazim and total carbendazim were high (half-lives of 1.61-2.46 days) and varied in the field cowpea samples because of the different weather conditions and planting patterns. Based on the definition of thiophanate-methyl, the terminal residues of total carbendazim in cowpea samples were below the maximum residue limits set by Japan for other legumes. The acute and chronic risk quotients of three analytes were 0.0-27.6% in cowpea samples gathered from all terminal residue treatments, which were below 100%. CONCLUSION: An optimized approach for detecting thiophanate-methyl and carbendazim in cowpeas was applied for the investigation of field-trial samples. The potential acute and chronic dietary risks of thiophanate-methyl, carbendazim and total carbendazim to the health of Chinese consumers were low. These results could guide the safe and proper use of thiophanate-methyl ...