Prediction of spontaneous preterm birth by cervical length in the first trimester of pregnancy: Comparison of two measurement methods

作者：Qiaoli Feng, Honglei Duan, Xiaoqing Ju, Kubi Appiah, Ka Man Yip, Yi‐Yun Tai, Qian Sun, Piya Chaemsaithong, Liona C. Poon · 发表于：Acta Obstetricia Et Gynecologica Scandinavica · 年份：2021 · DOI：10.1111/aogs.14138 · 被引用次数：18 · 研究领域：Preterm Birth and Chorioamnionitis、Reproductive tract infections research、Maternal and Perinatal Health Interventions

INTRODUCTION: Our objectives were to compare the single-line and two-line methods of cervical length measurement in the first trimester of pregnancy and to evaluate the potential value of the first trimester cervical length measured by the two methods in predicting spontaneous preterm birth. MATERIAL AND METHODS: weeks of gestation. Cervical length was measured by two methods: (i) a linear distance between the two ends of the glandular area around the endocervical canal (single-line method) and (ii) a sum of a linear distance from the internal os to the greatest cervical curvature and a linear distance from this point of the cervix to the external os (two-line method). The screening performance of the first trimester cervical length measured by the two different methods for the prediction of spontaneous preterm delivery was assessed by receiver-operating characteristics (ROC) curve analysis. The areas under the ROC (AUROC) were compared by De Long test. RESULTS: A total of 1484 consecutive singleton pregnancies were included in this study. Spontaneous preterm delivery at <37 and <32 weeks occurred in 75 cases (5.1%) and 12 cases (0.8%), respectively. The median cervical length measured by the single-line method was significantly shorter than that by the two-line method (33.5 vs 36.5 mm, p < .001). Compared with the term delivery group, the median cervical length measured by the two-line method was shorter in women with spontaneous delivery at <32 weeks of gestation (36.5 vs 3...