Berberine-induced TFEB deacetylation by SIRT1 promotes autophagy in peritoneal macrophages

作者：Yinghong Zheng, Jiayuan Kou, Pengyu Wang, Ting Ye, Zitong Wang, Ziyu Gao, Lin Cong, Manman Li, Bowen Dong, Wei Yang, Quanfeng Li, Hong Li, Rui Wang, Liming Yang · 发表于：Aging · 年份：2021 · DOI：10.18632/aging.202566 · 被引用次数：54 · 研究领域：Autophagy in Disease and Therapy、Cannabis and Cannabinoid Research、Berberine and alkaloids research

synthesis pathway and, in turn, promoting TFEB nuclear translocation and deacetylation. The functional regulation of SIRT1 and TFEB by berberine could be exploited as a potential therapeutic strategy for atherosclerosis.