An efficient construction of CN bond under catalyst‐free and room temperature conditions
作者：Jinpeng Zhang, Jing Liu, Lei Dai, Yuqian Ge, Linlin Xu, Yingying Xia, Lan Xu, Liangce Rong · 发表于：Journal of Heterocyclic Chemistry · 年份：2021 · DOI：10.1002/jhet.4250 · 被引用次数：5 · 研究领域：Synthesis of Indole Derivatives、Multicomponent Synthesis of Heterocycles、Axial and Atropisomeric Chirality Synthesis
Abstract An efficient and facile process for the construction of CN bond from 1,6‐conjugate addition reaction of 4‐arylidene‐2,6‐di‐tert‐butylcyclohexa‐2,5‐dien‐1‐one (or substituted 3‐[3,5‐di‐tert‐butyl‐4‐oxocyclohexa‐2,5‐dien‐1‐ylidene]indolin‐2‐one) and substituted 1,2,3,4‐tetrahydroisoquinoline (or substituted indoline) at room temperature was reported. The advantages of this reaction were catalyst‐free, mild condition, broad substrate scope, and environmentally benign process.