Correspondence Between Perceived Pubertal Development and Hormone Levels in 9-10 Year-Olds From the Adolescent Brain Cognitive Development Study

作者：Megan M. Herting, Kristina A. Uban, Marybel R. Gonzalez, Fiona C. Baker, Eric Kan, Wesley Kurt Thompson, Douglas Alan Granger, Matthew D. Albaugh, Andrey P. Anokhin, Kara Simone Bagot, Marie T. Banich, Deanna M. Barch, Arielle Baskin–Sommers, Florence J. Breslin, B.J. Casey, Bader Chaarani, Linda Chang, Duncan B. Clark, Christine C. Cloak, Robert Todd Constable, Linda Bauer Cottler, Rada K. Dagher, Mirella Dapretto, Anthony Steven Dick, Nico U.F. Dosenbach, Gayathri J. Dowling, Julie A. Dumas, Sarah Matthes Edwards, Thomas Ernst, Damien A. Fair, Sarah W. Feldstein-Ewing, Edward G. Freedman, Bernard F. Fuemmeler, Hugh P Garavan, Dylan G. Gee, Jay N. Giedd, Paul E.A. Glaser, Aimée Goldstone, Kevin Michael Gray, Samuel W. Hawes, Andrew C. Heath, Mary M. Heitzeg, John K. Hewitt, Charles J. Heyser, Elizabeth A. Hoffman, Rebekah S. Huber, Marilyn Ann Huestis, Luke Williamson Hyde, Maria Alejandra Infante, Masha Y. Ivanova, Joanna Jacobus, Terry L. Jernigan, Nicole R. Karcher, Angela R. Laird, Kimberly H. LeBlanc, Krista M. Lisdahl, Monica M. Luciana, Beatríz Luna, HERMINE H. M. MAES, Andrew T. Marshall, Michael J. Mason, Erin McGlade, Amanda Sheffield Morris, Bonnie J. Nagel, Gretchen N. Neigh, Clare E. Palmer, Martin P. Paulus, Alexandra S. Potter, Leon I. Puttler, Nishadi Rajapakse, Kristina M. Rapuano, Gloria M. Reeves, Perry Franklin Renshaw, Claudiu Schirda, Kenneth J. Sher, Chandni S. Sheth, Paul D. Shilling, Lindsay M. Squeglia, Matthew T. Sutherland, Susan Frances Tapert, Rachel L. Tomko, Deborah A Yurgelun-Todd, Natasha E. Wade, Susan R.B. Weiss, Robert A. Zucker, Elizabeth R. Sowell · 发表于：Frontiers in Endocrinology · 年份：2021 · DOI：10.3389/fendo.2020.549928 · 被引用次数：128 · 研究领域：Hypothalamic control of reproductive hormones、Sexual function and dysfunction studies、Hormonal and reproductive studies

Aim: To examine individual variability between perceived physical features and hormones of pubertal maturation in 9-10-year-old children as a function of sociodemographic characteristics. Methods: the pubertal development scale (PDS) and child salivary hormone levels (dehydroepiandrosterone and testosterone in all, and estradiol in females). Multi-level models examined the relationships among sociodemographic measures, physical features, and hormone levels. A group factor analysis (GFA) was implemented to extract latent variables of pubertal maturation that integrated both measures of perceived physical features and hormone levels. Results: PDS summary scores indicated more males (70%) than females (31%) were prepubertal. Perceived physical features and hormone levels were significantly associated with child's weight status and income, such that more mature scores were observed among children that were overweight/obese or from households with low-income. Results from the GFA identified two latent factors that described individual differences in pubertal maturation among both females and males, with factor 1 driven by higher hormone levels, and factor 2 driven by perceived physical maturation. The correspondence between latent factor 1 scores (hormones) and latent factor 2 scores (perceived physical maturation) revealed synchronous and asynchronous relationships between hormones and concomitant physical features in this large young adolescent sample. Conclusions: Sociodemograp...