VPS34 regulates dynamin to determine the endocytosis of mitochondria-targeted zinc oxide nanoparticles in human osteosarcoma cells

作者：Xiaoyu Pan, Guanping He, Bao Hai, Yu Liu, Lei Bian, Yong Lei, Hanwen Zhang, Chenlong Yang, Chuanchao Du, Tianli Mao, Yunlong Ma, Fei Jia, Xinyu Dou, Shuheng Zhai, Xiaoguang Liu · 发表于：Journal of Materials Chemistry B · 年份：2021 · DOI：10.1039/d1tb00226k · 被引用次数：18 · 研究领域：Nanoplatforms for cancer theranostics、Advanced Nanomaterials in Catalysis、Extracellular vesicles in disease

ZnO NPs enter into osteosarcoma cells via VPS34/dynamin 2 pathway and accumulated in mitochondria, initiating mitophagy and subsequent apoptosis.