Application of nanomaterials in the treatment of rheumatoid arthritis

作者：Miaomiao Zheng, Huiju Jia, Huangwei Wang, Linhong Liu, Zhesheng He, Zhiyong Zhang, Wenzhi Yang, Liang Gao, Xueyun Gao, Fuping Gao · 发表于：RSC Advances · 年份：2021 · DOI：10.1039/d1ra00328c · 被引用次数：70 · 研究领域：Rheumatoid Arthritis Research and Therapies、Bone and Joint Diseases、Nanoparticle-Based Drug Delivery

Rheumatoid Arthritis (RA) is a chronic autoimmune disease, which mainly causes inflammation of the synovial joints and destruction of cartilage and bone tissue. At present, a variety of clinical drugs have been applied in the treatment of rheumatoid arthritis. With the development of nanotechnology, more and more nano-drugs have been applied in the treatment of rheumatoid arthritis due to the unique physical and chemical properties of nanomaterials. Treatment of RA with nanomaterials can improve bioavailability and selectively target damaged joint tissue. In this review, we summarized the progress of the application of nanomaterials in the treatment of rheumatoid arthritis and also proposed challenges faced by nanomaterials in the treatment of rheumatoid arthritis.