A predictive model using left atrial function and B‐type natriuretic peptide level in predicting the recurrence of early persistent atrial fibrillation after radiofrequency ablation

作者：Zhenni Yang, Min Xu, Chuxu Zhang, Huannian Liu, Xiaoliang Shao, Yuetao Wang, Ling Yang, Junhua Yang · 发表于：Clinical Cardiology · 年份：2021 · DOI：10.1002/clc.23557 · 被引用次数：17 · 研究领域：Atrial Fibrillation Management and Outcomes、Cardiac Arrhythmias and Treatments、Cardiovascular Function and Risk Factors

AIM: A predictive model using left atrial function indexes obtained by real-time three-dimensional echocardiography (RT-3DE) and the blood B-type natriuretic peptide (BNP) level was constructed, and its value in predicting recurrence in patients with early persistent atrial fibrillation (AF) after radiofrequency ablation was explored. METHODS: A total of 228 patients with early persistent AF who were scheduled to receive the first circular pulmonary vein ablation (CPVA) were enrolled. Clinical data of patients were collected: (1) The blood BNP level was measured before radiofrequency ablation; (2) RT-3DE was used to obtain the left atrial (LA) time-volume curve; (3) The clinical characteristics, BNP level and LA function parameters were compared, and logistic regression was used to construct a prediction model with combined parameters; (4) The receiver operating characteristic (ROC) curve was used to examine the diagnostic efficacy of the model. RESULTS: (1) 215 patients with early persistent AF completed CPVA and the follow-up. After 3-6 months of follow-up, the patients were divided into sinus rhythm group (160 cases) and recurrence group (55 cases); (2) The recurrence group showed higher minimum LA volume index, diastolic ejection index, and preoperative BNP (all p ≤ .001), while the sinus rhythm group exhibited higher expansion index (PI) and left atrial appendage peak emptying velocity (p ≤ .001); (3) In univariate analysis, BNP level had the best diagnostic performance ...