Postoperative analgesic effects of the quadratus lumborum block III and transversalis fascia plane block in paediatric patients with developmental dysplasia of the hip undergoing open reduction surgeries: a double-blinded randomised controlled trial

作者：Congcong Huang, Xiaoguang Zhang, Chaoxuan Dong, Chunwei Lian, Jun Li, Lingzhi Yu · 发表于：BMJ Open · 年份：2021 · DOI：10.1136/bmjopen-2020-038992 · 被引用次数：20 · 研究领域：Anesthesia and Pain Management、Pediatric Pain Management Techniques、Hip disorders and treatments

OBJECTIVE: To evaluate the analgesic effectiveness of two novel regional nerve blocks in paediatric patients with developmental dysplasia of the hip (DDH) after open reduction surgeries. DESIGN: Prospective, double-blinded, randomised controlled trial. SETTING: 2 tertiary teaching hospitals in China between August 2017 and July 2018. PARTICIPANTS: 110 paediatric patients aged 2-10 years with DDH undergoing open reduction surgeries were recruited, 95 were randomised and 90 were included in the final analysis. INTERVENTIONS: Random assignment to quadratus lumborum block III (QLB III) group, transversalis fascia plane block (TFPB) group and the control (no region nerve block) group. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was the Face, Legs, Activity, Cry and Consolability (FLACC) Scale Scores. Secondary outcomes included perioperative opioid consumption, the time until first press of nurse-controlled analgesia/patient-controlled analgesia (NCA/PCA) pump and the total counts number of pressing, length of postanaesthesia care unit (PACU) stay, length of hospital stay, parental satisfaction with pain management and adverse events. RESULTS: Mean FLACC Scores were significantly lower in QLB III group and TFPB group while in the PACU and for 48 hours postoperatively, compared with control group (p<0.0001, p<0.0001, respectively). No differences were found for FLACC Scores between QLB III group and TFPB group, neither at rest (p=0.0402) nor while posture changing (...