Gut Bacteroides species in health and disease

作者：Hassan Zafar, Milton H. Saier · 发表于：Gut Microbes · 年份：2021 · DOI：10.1080/19490976.2020.1848158 · 被引用次数：1265 · 研究领域：Gut microbiota and health、Gastrointestinal motility and disorders、Diet and metabolism studies

The functional diversity of the mammalian intestinal microbiome far exceeds that of the host organism, and microbial genes contribute substantially to the well-being of the host. However, beneficial gut organisms can also be pathogenic when present in the gut or other locations in the body. Among dominant beneficial bacteria are several species of Bacteroides, which metabolize polysaccharides and oligosaccharides, providing nutrition and vitamins to the host and other intestinal microbial residents. These topics and the specific organismal and molecular interactions that are known to be responsible for the beneficial and detrimental effects of Bacteroides species in humans comprise the focus of this review. The complexity of these interactions will be revealed.