A review of methods for addressing components of interventions in meta-analysis

作者：Maria Petropoulou, Orestis Efthimiou, Gerta Rücker, Guido Schwarzer, Toshi A. Furukawa, Alessandro Pompoli, Huiberdina L. Koek, Cinzia Del Giovane, Nicolas Rodondi, Dimitris Mavridis · 发表于：PLoS ONE · 年份：2021 · DOI：10.1371/journal.pone.0246631 · 被引用次数：74 · 研究领域：Behavioral Health and Interventions、Digital Mental Health Interventions、Meta-analysis and systematic reviews

Many healthcare interventions are complex, consisting of multiple, possibly interacting, components. Several methodological articles addressing complex interventions in the meta-analytical context have been published. We hereby provide an overview of methods used to evaluate the effects of complex interventions with meta-analytical models. We summarized the methodology, highlighted new developments, and described the benefits, drawbacks, and potential challenges of each identified method. We expect meta-analytical methods focusing on components of several multicomponent interventions to become increasingly popular due to recently developed, easy-to-use, software tools that can be used to conduct the relevant analyses. The different meta-analytical methods are illustrated through two examples comparing psychotherapies for panic disorder.