Asymmetric Synthesis of Silicon-Stereogenic Monohydrosilanes by Dehydrogenative C–H Silylation

作者：Wei Yuan, Lijun You, Weidong Lin, Jie Ke, Yingzi Li, Chuan He · 发表于：Organic Letters · 年份：2021 · DOI：10.1021/acs.orglett.1c00029 · 被引用次数：78 · 研究领域：Organoboron and organosilicon chemistry、Catalytic Cross-Coupling Reactions、Catalytic C–H Functionalization Methods

An asymmetric synthesis of silicon-stereogenic monohydrosilanes by rhodium-catalyzed dehydrogenative C–H silylation is developed. The process is suitable for the synthesis of various asymmetrically trisubstituted 1 H -benzosiloles and 1 H -benzosilolometallocenes in good yields with excellent chemo-, regio-, and stereocontrol. These selected silicon-stereogenic 1 H -benzosilole compounds exhibit bright blue fluorescence and CPL (circular polarized luminescence) signals, which could be attractive to practitioners of materials science.