Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

作者：Zhuting Hu, Donna Leet, Rosa Lundbye Allesøe, Giacomo Oliveira, Shuqiang Li, Adrienne Luoma, Jinyan Liu, Juliet Forman, Teddy Huang, Julian Bryan Iorgulescu, Rebecca L. Holden, Siranush Sarkizova, Satyen Harish Gohil, Robert Allyn Redd, Jing Sun, Liudmila Elagina, Anita Giobbie‐Hurder, Wandi Zhang, Lauren E. Peter, Zoe B. Ciantra, Scott J. Rodig, Oriol Olive, Keerthi S. Shetty, Jason W. Pyrdol, Mohamed Uduman, Patrick C. Lee, Pavan Bachireddy, Elizabeth Iannotti Buchbinder, Charles H. Yoon, Donna S Neuberg, Bradley L. Pentelute, Nir Hacohen, Kenneth J. Livak, Sachet Ashok Shukla, Lars Rønn Olsen, Dan H. Barouch, Kai W. Wucherpfennig, Edward F. Fritsch, Derin B. Keskin, Catherine J. Wu, Patrick Alexander Ott · 发表于：Nature Medicine · 年份：2021 · DOI：10.1038/s41591-020-01206-4 · 被引用次数：548 · 研究领域：Immunotherapy and Immune Responses、vaccines and immunoinformatics approaches、CAR-T cell therapy research