Rezafungin: A Novel Antifungal for the Treatment of Invasive Candidiasis

作者：YoungYoon Ham, James S. Lewis, George R. Thompson · 发表于：Future Microbiology · 年份：2021 · DOI：10.2217/fmb-2020-0217 · 被引用次数：65 · 研究领域：Antifungal resistance and susceptibility、Fungal Infections and Studies、Nematode management and characterization studies

isolates. Available clinical data show robust safety and promising efficacy. Phase III trials will provide data on efficacy of rezafungin for the treatment of candidemia and invasive candidiasis and for the prevention of invasive fungal disease in blood and bone marrow transplant recipients. Rezafungin is a promising new candidate in the antifungal arsenal that opens up clinical possibilities based on its impressive half-life, such as early hospital discharge for stable patients and use as prophylaxis in immunocompromised patients.