Tumor microenvironment remodeling and tumor therapy based on M2-like tumor associated macrophage-targeting nano-complexes

作者：Shulan Han, Wenjie Wang, Shengfang Wang, Tingyuan Yang, Guifeng Zhang, Di Wang, Rui-Jun Ju, Yu Lu, Huimei Wang, Lianyan Wang · 发表于：Theranostics · 年份：2021 · DOI：10.7150/thno.50928 · 被引用次数：275 · 研究领域：Immune cells in cancer、Nanoplatforms for cancer theranostics、Phagocytosis and Immune Regulation

The nano-complexes facilitated baicalin, antigen, and immunostimulant delivery to M2-like TAMs, which polarized and reversed the M2-like TAM phenotype and remodeled the tumor microenvironment to allow killing of tumor cells.