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Inhibitory signaling sustains a distinct early memory CD8 + T cell precursor that is resistant to DNA damage

作者:Jonathan B. Johnnidis, Yuki Muroyama, Shin Foong Ngiow, Zeyu Chen, Sasikanth Manne, Zhangying Cai, Shufei Song, Jesse M. Platt, Jason M. Schenkel, Mohamed S. Abdel-Hakeem, Jean‐Christophe Beltra, Allison R. Greenplate, Mohammed-Alkhatim A. Ali, Kito Nzingha, Josephine R. Giles, Christelle Harly, John Attanasio, Kristen E. Pauken, Bertram Bengsch, Michael Paley, Vesselin T. Tomov, Makoto Kurachi, Dario A.A. Vignali, Arlene H. Sharpe, Steven L. Reiner, Avinash Bhandoola, F. Bradley Johnson, E. John Wherry · 发表于:Science Immunology · 年份:2021 · DOI:10.1126/sciimmunol.abe3702 · 被引用次数:92 · 研究领域:Immune Cell Function and Interaction、T-cell and B-cell Immunology、Immunotherapy and Immune Responses

An early memory CD8 + T cell precursor with distinct genome maintenance capacity depends on inhibitory receptor signaling.