Comprehensive circular RNA expression profiling constructs a ceRNA network and identifies hsa_circ_0000673 as a novel oncogene in distal cholangiocarcinoma

作者：Xin Zhao, Xinxue Zhang, Zhigang Zhang, Zhe Liu, Jiqiao Zhu, Shaocheng Lyu, Lixin Li, Ren Lang, Qiang He · 发表于：Aging · 年份：2020 · DOI：10.18632/aging.104099 · 被引用次数：14 · 研究领域：Circular RNAs in diseases、Cancer-related molecular mechanisms research、Cholangiocarcinoma and Gallbladder Cancer Studies

experiments indicated that inhibition of hsa_circ_0000673 suppressed the proliferation, migration, and invasion of CCA cells. This research provided a landscape of dysregulated circRNAs in dCCA and identified hsa_circ_0000673 as a potential biomarker and therapeutic target for dCCA.