Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial

作者：Javier Cortés, David W. Cescon, Hope S. Rugo, Zbigniew Ireneusz Nowecki, Seock‐Ah Im, Mastura Md Yusof, Carlos Gallardo, Oleg Lipatov, Carlos H. Barrios, Esther Holgado, Hiroji Iwata, Norikazu Masuda, Marco Torregroza Otero, Erhan Gökmen, Sherene Loi, Zifang Guo, Jing Zhao, Gursel Aktan, Vassiliki Karantza, Peter Schmid, F. Vidal Luis, Gomez Abuin Gonzalo, Diego Kaen, Kowalwszyn Ruben, Molina Matias, Varela Mirta, Sally Baron-Hay, Begbie Stephen, Clingan Philip, Loi Sherene, Sabanathan Dhanusha, Andrea Gombos, Donatienne Taylor, Carlos Roberto Barrios, Leandro Brust, Costa Fabiano, de Freitas Junior Ruffo, Roberto Hegg, Lacerda Domicio Carvalho, Lissa Fernando Cezar Toniazzi, Rocha Roberto Odebrecht, Scalabrini Neto Antonio Orlando, Silva Felipe, Cescon David, Danielle Charpentier, Ferrario Cristiano, Xinni Song, Yu Joanne, Alejandro Acevedo, Gallardo Carlos, Salas Claudio, Sanchez Cesar, Eduardo Yañez, Gomez Diaz Alvaro, Sanchez Jesus, Holeckova Petra, Kral Zdenek, Bohuslav Melichar, Katarína Petráková, Prausova Jana, Vesna Glavicic, Jakobsen Erik, Jensen Jeanette, Søren Linnet, Tamás Lörincz, Bonnefoi Herve, Isabelle Desmoulins, Goncalves Anthony, Hardy-Bessard Anne-Claire, Luís Teixeira, Blohmer Jens-Uwe, Fasching Peter, Dirk Forstmeyer, Nadia Harbeck, Huober Jens, Kaczerowsky Flores de Sousa Anna, Kurbacher Christian, Sibylle Loibl, Lueftner Diana, Park-Simon Tjoung-Won, Schumann Raquel Von, Pauline Wimberger, Chow Louis, Kwong Ava, Ngan Kai Cheong Roger, Peter Arkosy, Tibor Csőszi, Zsuzsanna Kahán, Landherr László, Mahr Karoly, Gábor Rubovszky, Crown John, Kelly Catherine, O'Reilly Seamus, Saverio Cinieri, DAlessio Antonietta, Ricevuto Enrico, Tomoyuki Aruga, Takaaki Fujii, Inoue Kenichi, Takashi Ishikawa, Ito Yoshinori, Tsutomu Iwasa, Iwata Hiroji, Yoshimasa Kosaka, Matsumoto Koji, Yasuo Miyoshi, Hirofumi Mukai, Seigo Nakamura, Naoki Niikura, Ohtani Shoichiro, Osaki Akihiko, Yasuaki Sagara, Suzuki Eiji, Masato Takahashi, Yuko Tanabe, Kenji Tamura, Koichiro Tsugawa, Junichiro Watanabe, Yamamoto Naohito, Yutaka Yamamoto, Teruo Yamauchi, Bustam Anita, M.Y. Mastura, Gomez Villanueva Angel, Juarez Ramiro Alejandro, Martinez Rodriguez Jorge, Morales-Vasquez Flavia, Reyes Contreras Jessica, Beelen Karin, Tjan-Heijnen Vivianne, Porter David, Ewa Chmielowska, Nowakowska-Zajdel Ewa, Nowecki Zbigniew, Radecka Barbara, Joanna Streb, Szczylik Cezary, Rafal Tarnawski, Zurawski Bogdan, Arkhipov Alexander, Natalia Fadeeva, Oleg Lipatov, Meshcheryakov Andrey, Moiseyenko Vladimir, Mukhametshina Guzel, Ahn Jin Hee, Im Seock-Ah, Lee Keun Seok, Park Kwong Hwa, Park Yeon Hee, Bermejo de las Heras Begona, Cortes Javier, Cruz Jurado Josefina, de la Cruz Merino Luis, Garcia Saenz Jose, Maria Gion, Esther Holgado, Zamora Adelantado Esther, Chien-Ting Liu, Mei-Ching Liu, Chiun‐Sheng Huang, Tsao Chao-Jung, Ling-Ming Tseng, Çağatay Arslan, Basaran Gul, İrfan Çiçin, Erhan Gokmen, Gunduz Seyda, Molinas Mandel Nil, Özgüroğlu Mustafa, Ozyilkan Ozgur, Sinan Yavuz, C. R. Williams Steve, Graham Janine, MacPherson Iain, Schmid Peter, Turner Nicholas, Tuthill Mark, Twelves Christopher, W Duncan, Hryhoriy Adamchuk, Oleksandr Berzoy, Bondarenko Igor, Kolesnik Oleksii, Olena Kolesnik, Komisarenko Hanna, Kryzhanivska Anna, Leshchenko Iurii, Nasonova Alla, Otchenash Natalya, Ponomarova Olga, Rusyn Andrii, Sergii Shevnya, Yaroslav V. Shparyk, Dmytro V. Trukhin, Grygorii Ursol, Vynnychenko Ihor, Sibel H. Blau, Madhu Chaudhry, Michael Chung, Patrick C. Ma, C. Scott, Jennifer Robinson Diamond, Gogineni Keerthi, Hargis Jeffrey, Hoskins Kent, Irvin William, Randa Loutfi, Lu Janice, Mena Raul, Moore Susan, Rita Nanda, Ira Oliff, Omene Coral, Panella Timothy, Panwalkar Amit, Brian J. Patson, Hope Rugo, Irina Rybalova, Schleider Michael, Siegel Robert, Simon Michael, Stampleman Laura, Sumrall Bradley, Tsai Michaela, Frances Valdes-Albini · 发表于：The Lancet · 年份：2020 · DOI：10.1016/s0140-6736(20)32531-9 · 被引用次数：1856 · 研究领域：Cancer Immunotherapy and Biomarkers、Breast Cancer Treatment Studies、Advanced Breast Cancer Therapies