A Retrospective Study on the Use of Chinese Patent Medicine in 24 Medical Institutions for COVID-19 in China

作者：Nan Zhang, Nannan Shi, Siyu Li, Guoxiu Liu, Yonglong Han, Li Liu, Xin Zhang, Xiang-Wen Kong, Bihua Zhang, Wenpeng Yuan, Yi Liu, Deqiang Deng, Minxia Zheng, Ying Zhang, Lihua Li, Xiaoping Wang, Jiankun Wu, Xiaolan Lin, Hua Nian, WU Xiao-hong, Hua Wang, Fang Liu, Hongli Wang, Hongshun Wang, Ying Liu, Li Liu, Weixin Zeng, Manqin Yang, Yanping Wang, Yanping Wang, Huaqiang Zhai, Yongyan Wang, Yongyan Wang · 发表于：Frontiers in Pharmacology · 年份：2020 · DOI：10.3389/fphar.2020.574562 · 被引用次数：19 · 研究领域：COVID-19 Clinical Research Studies、Climate Change and Health Impacts、Thermal Regulation in Medicine

Objective: This research aims to analyze the application regularity of Chinese patent medicine during the COVID-19 epidemic by collecting the names of the top three Chinese patent medicines used by 24 hospitals in 14 provinces of China in four time periods (January 20–22, February 16–18, March 01–03, April 01–03, 2020), and explore its contribution to combating the disease. Methods: 1) We built a database of the top three Chinese patent medicines used by 24 hospitals. 2) The frequency and efficacy distribution of Chinese patent medicine were analyzed with risk areas, regions, and hospitals of different properties as three factors. 3) Finally, we analyzed the differences in the use of heat-clearing and non-heat-clearing medicines among the three factors (χ 2 test) and the correlation between the Chinese patent medicine and COVID-19 epidemic (correlation analysis) with SPSS 23.0 statistical software. Results: 1) The heat-clearing medicine was the main use category nationwide during January 20–22, 2020. Meanwhile, there was a significant difference in the utilization rate of heat-clearing and non-heat-clearing medicine in different risk areas ( p < 0.01). 2) The variety of Chinese patent medicine was increased nationwide during February 16–18, 2020, mainly including tonics, blood-activating and resolving-stasis, and heat-clearing medicines. Meanwhile, there was a significant difference in the utilization rate of heat-clearing and non-heat-clearing medicine in the southern...