Predictors of illness course and health maintenance following inpatient treatment among patients with anorexia nervosa

作者：Deborah R. Glasofer, Alexandra F. Muratore, Evelyn Attia, Peng Wu, Yuanjia Wang, Hillary Minkoff, Teresa Rufin, B. Timothy Walsh, Joanna Steinglass · 发表于：Journal of Eating Disorders · 年份：2020 · DOI：10.1186/s40337-020-00348-7 · 被引用次数：72 · 研究领域：Eating Disorders and Behaviors、Body Image and Dysmorphia Studies、Bariatric Surgery and Outcomes

BACKGROUND: Anorexia nervosa (AN) is a life-threatening psychiatric disorder associated with significant medical and psychosocial impairment. Hospital-based behavioral treatment is an effective intervention in the short-term. However, relapse rates following discharge are high and thus, there is a need to identify predictors of longitudinal outcome. The current study provides information regarding illness course and health maintenance among patients with AN over 5 years following discharge from an eating disorder inpatient unit. METHODS: Participants were individuals with AN who were discharged from a specialized, inpatient behaviorally-based unit. Prior to discharge, height and weight were measured and participants completed self-report measures of eating disorder severity and general psychopathology (depression, anxiety, harm avoidance). Participants were contacted annually for self-report measures of weight, eating disorder severity and clinical impairment. Outcome was defined by illness course (body mass index (BMI) and clinical impairment during the 5 years) and health maintenance (categories of weight and eating disorder symptom severity) across follow-up, using all available data. Linear mixed models were used to examine whether demographic and clinical parameters at discharge predicted BMI and clinical impairment over time. Additional analyses examined whether these variables significantly influenced an individual's likelihood of maintaining inpatient treatment gains....