Nanosensor-Based Flexible Electronic Assisted with Light Fidelity Communicating Technology for Volatolomics-Based Telemedicine

作者：Han Jin, Junkan Yu, Shujing Lin, Shan Gao, Hao Yang, Hossam Haick, Changzhou Hua, Shengwei Deng, Tingqiang Yang, Yueli Liu, Wenfeng Shen, Xin Zhang, Xiaowei Zhang, Shan Shan, Tao Ren, Liwei Wang, Waifung Cheung, Wanlung Kam, Jianmin Miao, Di Chen, Daxiang Cui · 发表于：ACS Nano · 年份：2020 · DOI：10.1021/acsnano.0c06137 · 被引用次数：38 · 研究领域：Advanced Chemical Sensor Technologies、Advanced Sensor and Energy Harvesting Materials、Gas Sensing Nanomaterials and Sensors

Telemedicine provides an attractive vision for tele-monitoring human health conditions and, thus, offers the opportunity for timely preventing chronic disease. A key limitation of promoting telemedicine in clinic application is the lack of a noninvasive med-tech and effective monitoring platform, which should be wearable and capable of high-performance tele-monitoring of health risk. Here we proposed a volatolomics-based telemedicine for continuously and noninvasively assessing human health status through continuously tracking the variation of volatile markers derived from human breath or skin. Particularly, a nanosensor-based flexible electronic was specifically designed to serve as a powerful platform for implementing the proposed cost-effective healthcare. An all-flexible and highly packed makeup (all functional units were integrated in a 2*2*0.19 cm 3 plate) enables an electronic, compact configuration and the capability of resisting negative impact derived from customers’ daily movement. Notably, the nanosensor-based electronic demonstrates high specificity, quick response rate ( t 90% = 4.5 s), and desirable low detection limit (down to 0.117 ppm) in continuous tele-monitoring chronic-disease-related volatile marker (e.g., acetone). Assisted by the power saved light fidelity (Li-Fi) communicating technology, a clinic proof on the specifically designed electronic for noninvasively and uninterrupted assessing potential health risk (e.g., diabetics) is successfully impleme...