Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment

作者：Rui Zhang, Heng Li, Xianglei Zhang, Jian Li, Haixia Su, Qiukai Lu, Guangyu Dong, Huixia Dou, Chen Fan, Zhanni Gu, Qianwen Mu, Wei Tang, Yechun Xu, Hong Liu · 发表于：European Journal of Medicinal Chemistry · 年份：2020 · DOI：10.1016/j.ejmech.2020.113004 · 被引用次数：37 · 研究领域：Mast cells and histamine、Phosphodiesterase function and regulation、Asthma and respiratory diseases