A single-cell analysis of the molecular lineage of chordate embryogenesis

作者：Tengjiao Zhang, Yichi Xu, Kaoru S. Imai, Teng Fei, Guilin Wang, Bo Dong, Tianwei Yu, Yutaka Satou, Weiyang Shi, Zhirong Bao · 发表于：Science Advances · 年份：2020 · DOI：10.1126/sciadv.abc4773 · 被引用次数：38 · 研究领域：Single-cell and spatial transcriptomics、Congenital heart defects research、Pluripotent Stem Cells Research

cell types can be matched to E6.5-E8.5 stage mouse cell types and display conserved expression of limited number of transcription factors. This study provides a high-resolution single-cell dataset to understand chordate early embryogenesis and cell lineage differentiation.