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The Impact of Social Distancing for Severe Acute Respiratory Syndrome Coronavirus 2 on Respiratory Syncytial Virus and Influenza Burden

作者:Kathryn M. Edwards · 发表于:Clinical Infectious Diseases · 年份:2020 · DOI:10.1093/cid/ciaa1543 · 被引用次数:40 · 研究领域:Respiratory viral infections research、Pneumonia and Respiratory Infections、Congenital Diaphragmatic Hernia Studies

(See the Major Article by Friedrich et al on pages 2071–5, Brief Reports by Nolen et al on pages 2196–8 and Yeoh et al on pages 2199–202 and the Editorial Commentary by Covin and Rutherford on pages e993–4.) Each year pediatricians dread the annual arrival of respiratory syncytial virus (RSV) and influenza virus because they are both associated with increased respiratory illnesses and resultant hospitalizations. RSV is the major cause of pneumonia in young children and is responsible for yearly global morbidity and mortality [1, 2]. Influenza virus also has a major impact, with >100 pediatric deaths each year attributable to influenza in the United States, and the global burden is even more impactful [3, 4]. Thus, 3 articles appearing in this issue of Clinical Infectious Diseases demonstrate impressive declines in both RSV and influenza associated with mitigation strategies implemented in response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. They occur in 3 disparate regions of the world but provide some common perspectives [5–7]. Infants in the remote Yukon-Kuskokwim Delta (YKD) region of Alaska have the highest rates of RSV hospitalization in the United States, reaching 259 per 1000 infants during the winter season [8]. Since infants in the YKD region are all hospitalized in 1 hospital and since comprehensive viral surveillance for RSV has been conducted for >25 years, the impact of mitigation strategies on RSV burden can be comprehensively ...