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In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation

作者:Xiaomin Liang, Yeojin Park, Natalie DeForest, Hao Jia, Xiaofeng Zhao, Congrong Niu, Kelly Wang, Bill J. Smith, Yurong Lai · 发表于:Drug Metabolism and Disposition · 年份:2020 · DOI:10.1124/dmd.120.000163 · 被引用次数:24 · 研究领域:Drug Transport and Resistance Mechanisms、Liver Disease Diagnosis and Treatment、Liver physiology and pathology