WUSCHEL triggers innate antiviral immunity in plant stem cells

作者：Haijun Wu, Xiaoya Qu, Zhicheng Dong, Linjie Luo, Chen Shao, Joachim Forner, Jan U. Lohmann, Meng Su, Mengchu Xu, Xiaobin Liu, Lei Zhu, Jian Zeng, Sumei Liu, Zhaoxia Tian, Zhong Zhao · 发表于：Science · 年份：2020 · DOI：10.1126/science.abb7360 · 被引用次数：151 · 研究领域：Plant Molecular Biology Research、Plant Virus Research Studies、Plant-Microbe Interactions and Immunity

Building a safe space for stem cells The meristem, the collection of stem cells that builds plants, is resistant to viral infection. Wu et al. now show that WUSCHEL, a transcription factor that helps to sustain stem cell production in the shoot apical meristem of Arabidopsis , also protects that stem cell domain from viruses. WUSCHEL inhibited viral protein synthesis by repressing methyltransferases that regulate ribosomal RNA processing and ribosome stability. Science , this issue p. 227