Molecules from nature: Reconciling biodiversity conservation and global healthcare imperatives for sustainable use of medicinal plants and fungi

作者：Melanie‐Jayne R. Howes, Cassandra Leah Quave, Jérôme Collemare, Evangelos C. Tatsis, Danielle Twilley, Ermias Lulekal, Andrew W. K. Farlow, Liping Li, María Elena Cazar, Danna J. Leaman, Thomas A. K. Prescott, William Milliken, Cathie R. Martin, Marco Nuno De Canha, Namrita Lall, Haining Qin, Barnaby E. Walker, Carlos Alberto Vásquez Londoño, Bob Allkin, Malin Rivers, Monique S. J. Simmonds, Elizabeth A. Bell, Alex Battison, Juri Felix, Félix Forest, Christine J. Leon, China Williams, Eimear Nic Lughadha · 发表于：Plants People Planet · 年份：2020 · DOI：10.1002/ppp3.10138 · 被引用次数：221 · 研究领域：Essential Oils and Antimicrobial Activity、Phytochemistry and Bioactivity Studies、Ethnobotanical and Medicinal Plants Studies

Societal Impact Statement Plants and fungi have provided, or inspired, key pharmaceuticals for global health challenges, including cancer, heart disease, dementia, and malaria, and are valued as traditional medicines worldwide. Global demand for medicinal plants and fungi has threatened certain species, contributing to biodiversity loss and depletion of natural resources that are important for the health of humanity. We consider the evolving role of plants and fungi in global healthcare as new challenges to human health and to biodiversity arise. We present current and emerging scientific approaches, to uncover and preserve nature‐based health solutions for the future, through harmonization with biodiversity conservation strategies. Summary Non‐communicable diseases, including cardiovascular disease, cancer, and diabetes, are the main causes of deaths globally, and communicable diseases such as malaria and tuberculosis affect billions of people. Plants and fungi have provided key pharmaceuticals in our armory against these global health challenges, while in some regions of the world, they continue to have a central role in healthcare systems as traditional medicines. Consequently, global demand for plants and fungi in healthcare has threatened certain medicinal species, and is a driving factor in biodiversity loss. Yet the future of therapeutics from nature is evolving. Scientific advances are enabling the untapped potential of the world's plants and fungi to be explored for ...