The prevalence of psychiatric symptoms of pregnant and non-pregnant women during the COVID-19 epidemic

作者：Yongjie Zhou, Hui Shi, Zhengkui Liu, Songxu Peng, Ruoxi Wang, Qi Ling, Zezhi Li, Jiezhi Yang, Yali Ren, Xiuli Song, Lingyun Zeng, Wei Qian, Xiangyang Zhang · 发表于：Translational Psychiatry · 年份：2020 · DOI：10.1038/s41398-020-01006-x · 被引用次数：124 · 研究领域：Maternal Mental Health During Pregnancy and Postpartum、COVID-19 Impact on Reproduction、COVID-19 and Mental Health

Coronavirus disease 2019 (COVID-19) is rapidly spreading worldwide, with a staggering number of cases and deaths. However, available data on the psychological impacts of COVID-19 on pregnant women are limited. The purposes of this study were to assess the prevalence of psychiatric symptoms among pregnant women, and to compare them with non-pregnant women. From February 28 to March 12, 2020, a cross-sectional study of pregnant and non-pregnant women was performed in China. The online questionnaire was used to collect information of participants. The mental health status was assessed by patient health questionnaire, generalized anxiety disorder scale, insomnia severity index, somatization subscale of the symptom checklist 90, and post-traumatic stress disorder (PTSD) checklist-5. Totally, 859 respondents were enrolled, including 544 pregnant women and 315 non-pregnant women. In this study, 5.3%, 6.8%, 2.4%, 2.6%, and 0.9% of pregnant women were identified to have symptoms of depression, anxiety, physical discomfort, insomnia, and PTSD, respectively. However, the corresponding prevalence rates among non-pregnant women were 17.5%, 17.5%, 2.5%, 5.4%, 5.7%, respectively. After adjusting for other covariates, we observed that pregnancy was associated a reduced risk of symptoms of depression (OR = 0.23; 95% CI: 0.12-0.45), anxiety (OR = 0.26; 95% CI: 0.16-0.42), insomnia (OR = 0.19; 95% CI: 0.06-0.58), and PTSD (OR = 0.15; 95% CI: 0.04-0.53) during the COVID-19 epidemic. Our results ...