Oral delivery of anti-TNF antibody shielded by natural polyphenol-mediated supramolecular assembly for inflammatory bowel disease therapy

作者：Xinyu Wang, Junjie Yan, Lizhen Wang, Donghui Pan, Yuping Xu, Fang Wang, Jie Sheng, Xinxin Li, Min Yang · 发表于：Theranostics · 年份：2020 · DOI：10.7150/thno.47601 · 被引用次数：89 · 研究领域：Inflammatory Bowel Disease、Microscopic Colitis、Liver Diseases and Immunity

This polyphenol-based supramolecular nanoparticle is a promising platform for oral delivery of antibodies for the treatment of inflammatory bowel diseases, which may have promising clinical translation prospects.