The future of Extracellular Vesicles as Theranostics – an ISEV meeting report

作者：Carolina Soekmadji, Bo Li, Yiyao Huang, Haifang Wang, Taixue An, Chunchen Liu, Weilun Pan, Jing Chen, Lesley Cheung, Juan Manuel Falcón‐Pérez, Yong Song Gho, Harry Holthöfer, Minh T. N. Le, Antonio Marcilla, Lorraine O’Driscoll, Faezeh Shekari, Tang‐Long Shen, Ana Cláudia Torrecilhas, Xiaomei Yan, Fuquan Yang, Hang Yin, Yu Xiao, Zezhou Zhao, Xue Zou, Qian Wang, Lei Zheng · 发表于：Journal of Extracellular Vesicles · 年份：2020 · DOI：10.1080/20013078.2020.1809766 · 被引用次数：122 · 研究领域：Extracellular vesicles in disease、MicroRNA in disease regulation、Cell Adhesion Molecules Research

The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on "EVs in Clinical Theranostic". Here, we report the conclusions of roundtable discussions on the current advancement in the analysis technologies and we provide some guidelines to researchers in the field to consider the use of EVs in clinical application. The main challenges and the requirements for EV separation and characterization strategies, quality control and clinical investigation were discussed to promote the application of EVs in future clinical studies.