A reciprocal feedback of Myc and lncRNA MTSS1-AS contributes to extracellular acidity-promoted metastasis of pancreatic cancer

作者：Yuhang Hu, Fan Wang, Fengyu Xu, Kaifeng Fang, Zhi Fang, Xiaoming Shuai, Kailin Cai, Jinhuang Chen, Ping Hu, Ding Chen, Peng Xu, Chaojie Hu, Zhu Zeng, Jianxin Zhong, Wei Li, Jiang Tang, Mengqi Huang, Yong Zhao, Chunyou Wang, Gang Zhao · 发表于：Theranostics · 年份：2020 · DOI：10.7150/thno.49147 · 被引用次数：26 · 研究领域：Cancer-related molecular mechanisms research、RNA modifications and cancer、Cancer, Hypoxia, and Metabolism

The results implicated that a reciprocal feedback loop between Myc and MTSS1-AS contributed to the extracellular acidity-promoted metastasis of PC, and indicated that MTSS1-AS was a valuable biomarker and therapeutic target for PC.