Enantioselective Construction of Si‐Stereogenic Center via Rhodium‐Catalyzed Intermolecular Hydrosilylation of Alkene

作者：Tao He, Li‐Chuan Liu, Wenpeng Ma, Bin Li, Qing‐Wei Zhang, Wei He · 发表于：Chemistry - A European Journal · 年份：2020 · DOI：10.1002/chem.202003506 · 被引用次数：36 · 研究领域：Organoboron and organosilicon chemistry、Catalytic C–H Functionalization Methods、Catalytic Cross-Coupling Reactions

Catalytic, enantioselective synthesis of stereogenic silicon compounds remains a challenge. Herein, we report a rhodium-catalyzed regio- and enantio-selective intermolecular hydrosilylation of alkene with prochiral dihydrosilane. This new method features a simple catalytic system, mild reaction conditions and a wide functional group tolerance.