A Janus 3D DNA nanomachine for simultaneous and sensitive fluorescence detection and imaging of dual microRNAs in cancer cells

作者：Zezhou Yang, Xin Peng, Peng Yang, Ying Zhuo, Yaqin Chai, Wenbin Liang, Ruo Yuan · 发表于：Chemical Science · 年份：2020 · DOI：10.1039/d0sc02850a · 被引用次数：97 · 研究领域：Advanced biosensing and bioanalysis techniques、Nanopore and Nanochannel Transport Studies、Gold and Silver Nanoparticles Synthesis and Applications

hybridization (FISH) approach. Therefore, it could serve as persuasive evidence for supplying accurate information to better understand biological processes and investigate mechanisms of various biomolecules and subcellular organelles, resulting in the further validation of their function in tumor proliferation and differentiation. This strategy provided an innovative approach to design new generations of nanomachines with ultimate applications in bioanalysis and clinical diagnoses.