Elevated energy requirement of cone photoreceptors

作者：Norianne T. Ingram, Gordon Fain, Alapakkam P. Sampath · 发表于：Proceedings of the National Academy of Sciences · 年份：2020 · DOI：10.1073/pnas.2001776117 · 被引用次数：130 · 研究领域：Retinal Development and Disorders、Photoreceptor and optogenetics research、Photochromic and Fluorescence Chemistry

even in bright illumination. In mouse and human retina, rods greatly outnumber cones and consume more energy overall even in background light. In primates, however, the high density of cones in the fovea produces a pronounced peak of ATP utilization, which becomes particularly prominent in daylight and may make this part of the retina especially sensitive to changes in energy availability.