Pd‐Catalyzed Transfer of Difluorocarbene for Three Component Cross‐Coupling †

作者：Zhiwei Xu, Wei Zhang, Jin‐Hong Lin, Chuan‐Ming Jin, Ji‐Chang Xiao · 发表于：Chinese Journal of Chemistry · 年份：2020 · DOI：10.1002/cjoc.202000297 · 被引用次数：35 · 研究领域：Fluorine in Organic Chemistry、Cyclopropane Reaction Mechanisms、Catalytic Cross-Coupling Reactions

Summary of main observation and conclusion Outstanding accomplishments have been achieved in the chemistry of difluorocarbene, but transition‐ metal‐catalyzed transfer of difluorocarbene for coupling remains a challenging task. Herein, we describe a Pd‐catalyzed coupling of difluorocarbene with two aryl carbon centers to give difluoromethylenation products, which cannot be obtained by any previous difluorocarbene‐transformation method.