Prevalence and Associated Factors of Sarcopenia in Singaporean Adults—The Yishun Study

作者：Benedict Wei Jun Pang, Shiou Liang Wee, Lay Khoon Lau, Khalid Abdul Jabbar, Wei Ting Seah, Daniella Hui Min Ng, Queenie Lin Ling Tan, Kexun Kenneth Chen, Mallya Ullal Jagadish, Tze Pin Ng · 发表于：Journal of the American Medical Directors Association · 年份：2020 · DOI：10.1016/j.jamda.2020.05.029 · 被引用次数：129 · 研究领域：Nutrition and Health in Aging、Frailty in Older Adults、Body Composition Measurement Techniques

OBJECTIVES: To describe the normative values of sarcopenia among community-dwelling adults (≥21 years of age); compare the prevalence of sarcopenia using Asian Working Group for Sarcopenia criteria, 2014 (AWGS2014), Asian Working Group for Sarcopenia criteria, 2019 (AWGS2019), and European Working Group on Sarcopenia in Older People criteria, 2018 (EWGSOP2) guidelines; and identify factors associated with sarcopenia. DESIGN: Participants were recruited through random sampling. Sarcopenia assessments were performed using a dual-energy x-ray absorptiometry scan (muscle mass), handgrip test (muscle strength), and usual walking test (physical performance). Questionnaires were administered to evaluate lifestyle and cognition. SETTING AND PARTICIPANTS: In total, 542 community-dwelling Singaporeans were recruited (21‒90 years old, 57.9% women). METHODS: We assessed anthropometry, body composition, and questionnaire-based physical and cognitive factors, and estimated sarcopenia prevalence according to the AWGS2014, AWGS2019, and EWGSOP2 recommendations, and examined associations using logistic regression. RESULTS: According to AWGS2019, the Singapore population-adjusted sarcopenia prevalence was 13.6% (men 13.0%; women 14.2%) overall, and 32.2% (men 33.7%, women 30.9%) in those aged 60 years and above. The cut-offs derived from young adult reference group for low appendicular lean mass index were 5.28 kg/m2 for men and 3.69 kg/m2 for women (lower than AWGS recommended cut-off); for g...