TRPML1 channels initiate Ca 2+ sparks in vascular smooth muscle cells

作者：Pratish Thakore, Harry A. T. Pritchard, Caoimhín S. Griffin, Evan Yamasaki, Bernard T. Drumm, Conor P. Lane, Kenton M. Sanders, Yumei Feng, Scott Earley · 发表于：Science Signaling · 年份：2020 · DOI：10.1126/scisignal.aba1015 · 被引用次数：40 · 研究领域：Calcium signaling and nucleotide metabolism、Ion Channels and Receptors、Plant Stress Responses and Tolerance

Ca 2+ sparks that control arterial contractility and blood pressure require the lysosomal channel TRPML1.