Antifungal Susceptibility of Clinical Yeast Isolates from a Large Canadian Reference Laboratory and Application of Whole-Genome Sequence Analysis To Elucidate Mechanisms of Acquired Resistance

作者：Lisa R. McTaggart, Ana Cabrera, Kirby Cronin, Julianne V. Kus · 发表于：Antimicrobial Agents and Chemotherapy · 年份：2020 · DOI：10.1128/aac.00402-20 · 被引用次数：34 · 研究领域：Antifungal resistance and susceptibility、Fungal Infections and Studies、Yeasts and Rust Fungi Studies

To understand the epidemiology and susceptibility patterns of yeast infections in Ontario, Canada, we examined 4,715 clinical yeast isolates submitted to our laboratory for antifungal susceptibility testing from 2014 to 2018. Candida albicans was the most frequently submitted species (43.0%), followed by C. glabrata (21.1%), C. parapsilosis (15.0%), and C. tropicalis (6.2%). Twenty-three other Candida spp.