Biocatalytic membrane: Go far beyond enzyme immobilization

作者：Jianquan Luo, Siqing Song, Hao Zhang, Huiru Zhang, Jinxuan Zhang, Yinhua Wan · 发表于：Engineering in Life Sciences · 年份：2020 · DOI：10.1002/elsc.202000018 · 被引用次数：81 · 研究领域：Electrochemical sensors and biosensors、Enzyme Catalysis and Immobilization、Advanced biosensing and bioanalysis techniques

Biocatalytic membrane takes advantages of reaction-separation integration as well as enzyme immobilization, which has attracted increasing attentions in online detection and biomanufacturing. However, the high preparation cost, inferior comprehensive performance, and low stability limit its applications. Thus, besides enzyme immobilization, more efforts should be made in biocatalytic membrane configuration design for a specific application to enhance the synergistic effect of reaction and separation and improve its operating stability. This review summarized the recent progress on biocatalytic membrane preparation, discussed different membrane configurations for various applications, finally proposed several challenges and possible solutions, which provided directions and guides for the development and industrialization of biocatalytic membrane.