Effect of low-intensity exercise therapy on the hospitalized patients with chronic schizophrenia

作者：Jinglian Gu, Haiying Min, Ying Shen, Yanmin Shen · 年份：2016 · DOI：10.3760/cma.j.issn.1674-2907.2016.19.009 · 研究领域：Tryptophan and brain disorders

Objective To investigate the effects of the low-intensity exercise therapy on physical and mental health in hospitalized patients with chronic schizophrenia. Methods According to the random number table, a total of 90 inpatients with chronic schizophrenia were divided into intervention group(45 cases) and control group(45 cases). Both groups were treated with routine treatment and care, and the intervention group received extra exercise therapy for 3 months. Physiological indexes of blood pressure (both systolic and diastolic blood pressure, SBP and DBP), biochemical parameters of blood lipids including total cholesterol(TC), triglyceride(TG) and Positive and Negative Syndrome Scale(PANSS) scores were compared before and after intervention. Results After 3months′ intervention, SBP(121±9)mmHg and DBP(82±7)mmHg of intervention group were lower than the control group (t=-4.353, -2.648; P<0.01). TC(4.08±0.53)mmol/L and TG(0.90±0.21)mmol/L of the intervention group were lower than the control group (t=-4.517, -2.734; P<0.05). Total score of PANSS (63.93±5.78)points and its 4 sub scales including positive scale (14.65±2.71)points, negative scale (13.44±2.40)points, and general psychopathology scale (35.84±3.78)points were lower than the control group (t=-10.521, -4.174, -7.256, -8.055; P<0.01). Conclusions Low-intensity exercise therapy could promote the physical and mental health of the hospitalized patients with chronic schizophrenia. Key words: Schizoph...