Investigation of the remote acyl group participation in glycosylation from conformational perspectives by using trichloroacetimidate as the acetyl surrogate

作者：Ke Xu, Qingmin Man, Yang Zhang, Jia Guo, Yichu Liu, Zunyun Fu, Yueyue Zhu, Yingxia Li, Mingyue Zheng, Ning Ding · 发表于：Organic Chemistry Frontiers · 年份：2020 · DOI：10.1039/d0qo00363h · 被引用次数：28 · 研究领域：Carbohydrate Chemistry and Synthesis、Glycosylation and Glycoproteins Research、Chemical Synthesis and Analysis

The remote acyl group participation in glycosylation was studied by using trichloroacetimidate as the acetyl surrogate. The bridging participation intermediates were systematically trapped, and DFT calculations were applied to explain the results.