Effects of Exercise Training Interventions on Executive Function in Older Adults: A Systematic Review and Meta-Analysis

作者：Feng‐Tzu Chen, Jennifer L. Etnier, Kuei‐Hui Chan, Ping-Kun Chiu, Tsung-Ming Hung, Yu‐Kai Chang · 发表于：Sports Medicine · 年份：2020 · DOI：10.1007/s40279-020-01292-x · 被引用次数：267 · 研究领域：Dementia and Cognitive Impairment Research、Physical Activity and Health、Traumatic Brain Injury Research

BACKGROUND: Chronic exercise training has been shown be to positively associated with executive function (EF) in older adults. However, whether the exercise training effect on EF is affected by moderators including the specific sub-domain of EF, exercise prescription variables, and sample characteristics remains unknown. OBJECTIVES: This systematic and meta-analytic review of randomized controlled trials (RCTs) investigated the effects of exercise training on EF in older adults and explored potential moderators underlying the effects of exercise training on EF. METHODS: In accordance with the PRISMA guidelines, the electronic databases MEDLINE (PubMed) and EMBASE (Scopus) were searched from January 2003 to November 2019. All studies identified for inclusion were peer-reviewed and published in English. To be included, studies had to report findings from older (> 55 years old), cognitively normal adults or adults with mild cognitive impairment (MCI) randomized to an exercise training or a control group. The risk of bias in each study was appraised using the Cochrane risk-of-bias tool. Fixed-effects models were used to compare the effects of exercise training and control conditions on EF assessed at baseline and post-intervention. In addition, subgroup analyses were performed for three moderators (i.e., the specific sub-domain of EF, exercise prescription variables, and sample characteristics). RESULTS: Thirty-three RCTs were included. Overall, exercise training was associated w...